The electrophysiology core facility (ePHYS) has acquired a high-density multielectrode array (HD-MEA) based on CMOS technology and will soon provide services around this innovative technology.

Equipment

Accura 3D	BioCAM DupleX

• 4096 electrodes for simultaneous extracellular recording
• Suitable for neuronal cell culture, brain organoids and brain slices
• Upgrade with 3D-electrode chip for a deep access of cerebral organoids and other tissues

The core facility uses the HD-MEA system from 3Brain.

Readouts

• Spike
• Local field potential (LFP)
• Evoked synaptic activity

Assays

• Functional characterization of 2D and 3D models of human iPSCs
• Phenotyping screening
• Neuronal network activity
• Synaptic plasticity