Experimental models

Rodent brain slices	Zebrafish Larva

Readouts

• Intrinsic membrane properties • Action potential firing and excitability • Microcircuit synaptic connectivity • Synaptic plasticity • Ion channel biophysical properties • Morphological neuron reconstruction

Applications

Highlights

Characterization of preclinical models recapitulating human disease

Functional and morphological alterations in a mouse model of epilepsy Publication

Optogenetics

Activation of light-sensitive ion channels (opsins) to control neuron activity  Publication

Services

• Generation of full data set : experiments design, data acquisition and analysis
• Access to the facility setup for trained electrophysiologists